Initially, the symptoms of this disease are non-distinguishable to neonatal jaundice. Children and infants with biliary atresia begin to show particular symptoms of the disease from 2-8 weeks of their birth onwards. When the bile fails to drain from the liver due to blockage, it starts to build up inside and causes damage and scarring of liver cells. The symptoms include: Jaundice. Itchiness. Pale stool. Dark or orange urine. Swollen abdomen. Poor absorption of nutrients causing delay in growth and weight loss.DFDAFF
The causes and reasons of biliary atresia are not completely understood. But in some cases, the incomplete development of bile duct in the mother’s womb could be a reason, or the bile ducts could be affected due to a virus infection in perinatal period. Also, there are no links to medications taken during pregnancy. It is evident that 10-15% of infants with the disease are born with abnormalities in the: Heart. Blood vessel (inferior vena canal anomalies). Intestinal (malrotation). Spleen (Polysplenia)
Diagnosis is made based on symptoms, physical examination, and medical history of the patient using blood tests, biopsy of liver, and imaging for a better and clearer picture. Blood tests confirm liver function abnormalities and identify the cause of jaundice. X-rays Ultrasound Blood tests Biopsy Surgery
Removal of damaged ducts The surgeon removes the damaged ducts outside the liver and identifies smaller ducts still open and draining bile. A loop of intestine is then attached to these open ducts for proper drainage and flow of bile from healthy ducts. Long-term antibiotic therapy It is prescribed for avoiding any infection along with additional medications to maximize the success of the operation. In cases where Kasai procedure is not successful, liver transplant is the only solution. Success of the procedure is dependent on: Age: Younger the infant, greater the success rates of operation. Extent of Liver damage. Number and size of functional and healthy ducts. Experience of the surgical and medical team
To prevent the occurrence of this disease, one should take care of: Health. Sleep hours. Physical fitness. Eating habits.
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